The Panter`s webstore
Go here to see all disease treatment and fitness improvement products
Natural products to help against hormonal, metabolic and nervous diseases
On this site you will find a presentation of advanced natural products to help cure or alleviate diseases in the hormonal system, metabolic ballance and nervous system, and problems often liked to such diseases, like obesity or edema.
Please click on the banners or links to learn more or order a product. Please also bookmark this site and look for updates at a later time.
Further down there is some information about alkaloids, components found in many plants. To find a list of other information articles please click here.
help for depression, anxiety, sleeplessness, restlessness and other mental problems
SLEEP PROBLEMS - Solaray Sleep Blend Sp 17 and other natural products to optimize sleep: This product contains valerian root extract, a long proven means against sleep problems.
Another product you will find here is 5-hydoxy thryptophan capsules. This substanse improves sleep by inceasing the amount of serotonine in the brain.
Click here to lern more or buy - Solaray Sleep Blend
DEPRESSION and mood swings - Exulin: In addition to psychological factors, low levels of neurotransmittors may cause depression and mood disorders. This product may help to elevate the levels of these substances in the central nervous system and thus help against depressive and mood related symptoms.
Click here to buy or learn more: Exulin
GABA DEFICIENCY - Moderex GABA: - Trouble relaxing, insomnia, painful arthritis-like symptoms, high blood pressure, anxiety are symptoms caused by lack of GABA. By GABA deficiency, two or more of these symptoms may occure. GABA is an important neurotransmitter. This product may help.
Click here to buy or learn more: Moderex GABA
SEROTONINE DEFICIENCY - Seronex: - Depression, anxiety, pain in joints or muscles (fibromyalgia), attention problems, migraine, insomnia, panic attacks or mood swings - Some or all of of these symptoms occur by low serotonine levels in the nervous system. This medicine may increase the serotonine levels to help.
Click here to buy or learn more: Seronex 5-HTP
TENSION, STRESS AND ANXIETY- Here is exhibited a natural drug that helps you to rlieve tension and stress, but also have an effect against anxiety. By going through this link you can find other herbel drugs too against tension and stress, and drugs more specifically targeted at anxiety.
ADD/ADHD - consentration and cognitive problems - Listol:Gives ingredients that help to balance the concentration of working sybstances in the brain and thereby helps for these problems.
Click here to learn more or buy -
ADD/ADHD - memory, consentration and cognitive problems:This supplemsnt gives ingredients that help to balance the concentration of working sybstances in the brain and thereby helps for these problems.
CEREBRAL PALCY - neurologic motoric problems- Vitarin: This preparation of vitamins, minerals and natural stimulants will support and strengthen the nervous system, the muscles and the bone structures of people suffering from cerebral palcy or motoric dysfunctions caused by nerve damage.
Click here to buy or learn more or buy - Vitarin
ALTZHEIMER'S DISEASE- Progressive 17: This natural drugs supplies compounds that effectivizes the brain function and help to slow down brain cell damage.
Altzheimer's - Progressive 17
DEMENTIA - confusion, memory loss - cognitive problems cyntol: This product is formulated to alleviate these symptoms also when they have other causes then Altzheimers.
Please click here to learn more or buy -Cyntol
Help for metabolic, systemic and hormonal imbalances
THYROID DEFICIENCY - Thyax thyroid stimulant: Helps against sluggish thyroid production and associated problems like: constant fatigue, over-wight, cold limbs, low blood pressure, yellowish skin color, dry skin and hair, impaired memory, depressive mood, sugar cravings, dimmished circulation, itching or rashes, lacy colon
Click here to buy or learn more: Thyax
Diabetes mellitus type 2 - Glucose M2:This product is not curative for diabetes type 2, but it enhances the ability to adjust the blood sugar levels towards a normal valuie.
Please click here to learn more or buy - GlucoseM2
HELP FOR EDEMA - Capisette oral pills- Edama is often linked to metabolic conditions or to inflammatory reactions. Capicette helps against edema by reducing inflammatory reactions and by aiding the circulation of blood and lymph fluid through the tissues.
Please click here to learn more or buy - Capicette
HELP FOR EDEMA - PYCNOGENOL- Pycnogenol is a anti-oxydative extract from the French marine pine tree bark that has shown good effect against edema. Pycnogenol also has a general revitalizing effect on many organ systems.
Please click here - Twinlab Pycnogenol, 50mg
Edema is also often linked to heart conditions please click here to find natural remedies for heart problems
There are many mechanical accessories available to treat edema, to see these, pleace click here
Help to increase the production of growth hormone -human growth hormone has proved to help regain skin thickness, muscle intactness, a jouvenile muscle/fat-ratio and other properties of youth:
Avlimil Complete - to improve female hormone levels giving stronger feelings, more robust sexual physiology and less menstrual problems- These pills make you more lusty for sex mentally and physically and boost your total erotic pleasure. They strengthen vaginal lubrication and other aspects of the female sexual physiology. Furthermore they will lesson menstrual problems.
ANEMIA / Low red blood cell count- Advena - A drug containing iron, other minerals and vitamins that nourishe and stimulate the building of red blood cells.
Click here to buy or learn more or buy - Advena
HEAD ACHE and migrene - Viaprene:This pills calm down tesnion in blood vessels and musculat tension that often cause heaf ache. They also contain herbal analgesic ingredients to directly alleviate ache.
Click here to buy or learn more - Viaprene
Please go here to find products against general pain, colic, stomach pain, sciatica
Help against over-weight / obesity
ProShapeRx - a multy-active slimming helper - This product can help you get slimmer by means of several actions, for example lovering of calory uptake, increasing of fat burning and reduction of a too eager appetite. Contains Hoodia Gordonii.
Exitor - to enhance your burning of fat and make you feel more vital: This product works by increasing fat burning and increasing your energy levels to render you more active than before. This product does not affect uptake of fat and sugar from the intestines.
Please click here to learn more or buy - Exitor
General stores for natural drugs
To find all natural drugs to treat common diseases, please click here
To find products to improve sexual life - please click here
For cosmetics, anti-aging, skincare products and fashion clothes, please go here
CURE OR SUPPORT for many specific diseases - Medicines to be taken by mouth: Acne, aging symptoms, AIDS, allergies, Alzheimers disease/dementia, angina, arthritis (osteoarthritis), arthritis (rheumatoid arthritis), asthma, attention deficit disorder (ADD), breast cancer, burns, carpal tunnel syndrome, cholesterol, cronic bronchitis, chronic cough, chronic fatigue sydrom, cognitive problems, colds and flue, congestive heart failure (CHF), Crohn`s disease, depression, diabetes mellitus type 1, diabetes mellitus type 2, eczema, edema, endometriosis, fatigue, fibromyalgia, hair loss, herpes simplex, hyperlipidemia, hypertention, obesity, otitis media, osteoporosis
Click here to find the right product
SKIN TREATMENT PRODUCTS and quality cosmetics for reduced prizes: In this collection you will find products for any specific skin treatment need, examples: Skin aging, acne, scars, rashes, sun-damage, cellulites, thin skin, edema, miscolored skin, rosacea, psoriasis, and more. You also find all cosmetic products from all the leading houses in the world.
Bulk herbs, teas, bath and body, aromatherapy - If you need separate herbs or preparations of separate herbs for some medical purpose, to use as spices in cooking, or for other purposes, you will find anything you need here. The store you get into does not only contain herbs, but also a lot of other products of many cathegories, like: Theas, cofees, spices, bath and body products, aromatherapy products, skincare items.
Medical and nursing equipment
Equipment for medical treatment and nursing of many kinds: Equipment for blood sugar monitoring and diabetic articles, enema equipment, orthopaedic items, catheters and urinary support,equipment for cardiac and circulatory support, blood pressure monitors, respiratory items, exercise gears, items for ulcer and injury nursing, and much more.
Items to prevent disease and improve well-being
Most people benefit from a daily surplus of vitamins and minerals for prevention of diseases and enhancement of general well-being.
Feel and look younger, reverse aging - human growth hormone has proved to help regain skin thickness, muscle intactness, a jouvenile muscle/fat-ratio and other properties of youth:
VITAMINS/MINERALS - Balance point: This product is an excellent source of vitamins, trace minerals and antioxydants for persons with an average need. As a result of these added nutrients and minerals, your body will have more oxygen at the cellular level - resulting in elevated levels of energy and a more active lifestyle. The product also purifies the fluids in your body. This in turn will make your skin look better and you feel younger.
Click here to learn more or buy - balance Point for Men
Click here to learn more or buy - balance Point for Women
CALCIUM SURPLUS - Activa Coral Calcium: Activa coral calcium gives you the extra amount of calsium most people need in a form that is taken up extreemely easy from your digestive system. It also regulates your body Ph to a favourable alcaline level. Most people have a too acid ph, which is very unfavourable to the general health.
Click here to buy or learn more: Activa
OMEGA DAILY - Omega-3-supplement: Omega-3-fatty acids are vital for the health of the blood circulation, joints and digestive system, and the diet of many people is in short of omega-3.
Please lick here to learn more or buy - Omega daily
GENERAL VITAMINE AND MINERAL STORE: Here you will find preparations of vitamins and minerals for all needs.
To see noni, mangosteen, goji, acai juices and, glyconutrients - please click here
To find supplements for body-building and training - please click here
ABOUT AMINES AND ALKALOIDS
What are amins and alkaloids
An amine contains a nitrogen atom that is bounded to at least one carbon atom, and where the other bindings go to either a hydrogen atom or other carbon atoms.
Complex amins are usully called alkaloids. In alkaloids the nitrogen atom has at least two bindings to carbon atoms, and at least one of these is the beginning of some complex chain or ring structure. The nitrogen atoms can take up a proton from an acid, and thus these compounds act as a base. Because of this chemical property, amins and alkaloids are powerful actors in the human body. Many are potent poisons, some are neurotransmotters or hormones. Many of them are used in medicine to cure diseases, to alleviate symptoms or modify physiological, mechanisms. Alkaloids most often has their effect in the nervous system.
usually derivatives of amino acids, and many have a bitter taste. They are found
as secondary metabolites in plants (e.g. potatoes and tomatoes), animals (e.g.
shellfish) and fungi. Many alkaloids can be purified from crude extracts by
Effects and uses of alkaloids
Here are some alkaloids listed according to their main mediacal or biological effects. Some alkaloids have several effects and are therefore listed more than once.
Hormons or neurotransmitter substances in the body or precursors for these: Dopamine, choline, serotonine, acetylcholine
Strong tasting elements in food or spices: Piperine
Acting against inflammation, fever or pain: Quinine
Anti-microbial acting used to cure infections: Quinine (against malaria)
Very poisenous alkaloids: Sanguinarine, muscarine, solanine, coniine, cytisine, aconitine, neurine
Very poisonous alkaloids that are used in very small amounts in some medicines to improve heart function, relaxe muscles or for other puposes: Strychnine, sanguinarine, atropine, scopalamine
Cell poisons, disturbing cell division, used as cytostatica to kill cancer cells or to help cure other diseases with exaggerated cell proliferation: Vinblastine, vincristine.
Nervous stimulants that effects both emotions and various organs: Yohimbine
Central nervous system stimulants enjoyed in food and beverages. Some are used to increase metabolism and help against over-weight: Caffeine, theobromine, theophylline, guaranine
Central nervous stimulaqting and addictive narcotics. Some are enjoyed legally or illegally, and some have uses in medicine. Ephedrine, amphetamine, nicotine, thebaine
Anti-depressants, monoamine oxidase inhibitors: Harmine, harmaline
Halusinogenic narcotics: Mescaline, scopalamine, harmaline, dymetyltryptamine, psilocybine, lysergic acid, lysergic acid diethylamide (LSD)
Sedating and addictive narcotics that are also used medicinally as analgesics (pain relievers) or anaesthetics; Morphine, thebaine, papaverine, narcotine, berberine, scoplamine
Sedating agents with antipsychotic or other specific actions: Reserpine.
Sedating or muscle relaxant alkaloids, used against cough and other medical purposes: Codeine, noscapine
Alkaloids with various physiological stimulating or relaxing effects upon smooth muscles and glands, used in medical treatments: Pilocarpine, Ergoline (migraine treatment)
Chemical grouping of alkaloids
Alkaloids kan be grouped chemically according to some chemical compound they resamble, and that they often are produced from by plants animals or pharmacological industry.
Pyridine group: piperine, coniine, trigonelline,
arecaidine, guvacine, pilocarpine, cytisine, nicotine, sparteine, pelletierine.
Pyrrolidine group: hygrine, cuscohygrine, nicotine
Tropane group: atropine, cocaine, ecgonine, scopolamine
Quinoline group: quinine, quinidine, dihydroquinine, dihydroquinidine, strychnine, brucine, veratrine, cevadine
Isoquinoline group: The opium alkaloids (morphine, codeine, papaverine, narcotine, sanguinarine, narceine,berberine)
Phenethylamine group: mescaline, ephedrine, dopamine, amphetamine
Tryptamines: DMT, N-methyltryptamine, psilocybin, serotonin
Ergolines: the ergot alkaloids (ergine, ergotamine, lysergic acid, etc.)
Beta-carbolines: harmine, harmaline, yohimbine, reserpine, emetine
Xanthines: caffeine, theobromine, theophylline
Aconite alkaloids: aconitine
Steroids: solanine, samandaris (quaternary ammonium compounds): muscarine, choline, neurine
Vinca alkaloids: vinblastine, vincristine.
Physical properties of alkaloids
Molecular weight 100-900
Those without oxygen atoms in the structure are usually liquid at ordinary temperature (e.g. nicotine, sparteine, coniine)
Those with oxygen atoms are crystalline (e.g. berberine)
Basicity depends on the availability of lone pairs of electrons on the N atom & the type of heterocycle and substituents.
Ability to form salts with mineral acids (e.g. with HCl, H2SO4, HNO3) or organic acids (e.g. tartrates, sulfamates, maleates)
(Most of this information is compiled form wikipedia.org)
ABOUT SOME SPECIFIC ALKALOIDS
Piperine - the tasting element in pepper
Piperine is the alkaloid responsible for the
pungency of black pepper along with chavicine (an isomer of piperine). It has
also been used in some forms of traditional medicine and as an insecticide.
The pungency caused by capsaicin and piperidine is caused by activation of the heat and acidity sensing TRPV ion channel TRPV1 on nociceptors (pain sensing nerve cells).
Piperine has also been found to inhibit human CYP3A4 and P-glycoprotein, enzymes important for the metabolism and transport of xenobiotics and metabolites (PMID 12130727). In animal studies, piperine also inhibited other enzymes important in drug metabolism (PMID 3917507, PMID 8347144). By inhibiting drug metabolism, piperine may increase the bioavailability of various compounds. Notably, piperine may enhance bioavailability of curcumin by 2000% in humans (PMID 9619120).
Due to its effects on drug metabolism, piperine should be taken cautiously (if at all) by individuals taking other medications.
Dopamine - a neurotransmitter and local brain hormone
Dopamine is a phenethylamine naturally produced by
the human body. In the brain, dopamine functions as a neurotransmitter,
activating the five types of dopamine receptor - D1, D2, D3, D4 and D5, and
their variants. Dopamine is produced in several areas of the brain, including
the substantia nigra.
Dopamine is also a neurohormone released by the hypothalamus. Its main function as a hormone is to inhibit the release of prolactin from the anterior lobe of the pituitary.
Dopamine can be supplied as a medication that acts on the sympathetic nervous system, producing effects such as increased heart rate and blood pressure. However, since dopamine cannot cross the blood-brain barrier, dopamine given as a drug does not directly affect the central nervous system. To increase the amount of dopamine in the brains of patients with diseases such as Parkinson's disease and Dopa-Responsive Dystonia, L-DOPA (levodopa), which is the precursor of dopamine, can be given because it can cross the blood-brain barrier.
Serotonine - an important neurotransmitter
Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine neurotransmitter synthesized in serotonergic neurons in the central nervous system (CNS) and enterochromaffin cells in the gastrointestinal tract of animals including humans. Serotonin is also found in many mushrooms and plants, including fruits and vegetables.
In the central nervous system, serotonin is believed to play an important role in the regulation of anger, aggression, body temperature, mood, sleep, vomiting, sexuality, and appetite. Low levels of serotonin may be associated with several disorders, namely increase in aggressive and angry behaviors, clinical depression, obsessive-compulsive disorder (OCD), migraine, irritable bowel syndrome, tinnitus, fibromyalgia, bipolar disorder, anxiety disorders and intense religious experiences. If neurons of the brainstem that make serotonin—serotonergic neurons—are abnormal, there is a risk of sudden infant death syndrome (SIDS).
Coline - an important nutrient
Choline is an organic compound, classified as an essential nutrient and usually grouped within the Vitamin B complex. This natural amine is found in the lipids that make up cell membranes and in the neurotransmitter acetylcholine. Adequate intakes for this micronutrient of between 425 to 550 milligrams daily, for adults, have been established by the Food and Nutrition Board of the Institute of Medicine of the National Academy of Sciences.
Coline is used in many alternative drugs to support the function of the nervous system, and the ability of tissue to heal from damage.
Acetylcoline - an important neurotransmittor
Acetylcholine is an ester of acetic acid and choline with chemical formula CH3COOCH2CH2N+(CH3)3. This structure is reflected in the systematic name, 2-acetoxy-N,N,N-trimethylethanaminium.
The chemical compound acetylcholine, often abbreviated as ACh, was the first neurotransmitter to be identified. It is a chemical transmitter in both the peripheral nervous system (PNS) and central nervous system (CNS) in many organisms including humans. Acetylcholine is the neurotransmitter in all autonomic ganglia. In layman's terms, it is a chemical that allows neurons to communicate with each other within humans and other organisms.
Quinine - treating fever, inflammation, pain and malaria
Quinine is a natural white crystalline alkaloid
having antipyretic (fever-reducing), antimalarial, analgesic (painkilling), and
anti-inflammatory properties and a bitter taste. It is a stereoisomer of
Quinine was the first effective cure for falciparum malaria, appearing in therapeutics in the 17th century. It remained the antimalarial drug of choice until the 1940s, when other drugs took over. Since then, many effective antimalarials have been introduced, although quinine is still used to treat the disease in certain critical situations. Quinine is available with a prescription in the United States. Quinine is also used to treat nocturnal leg cramps and arthritis, and there have been attempts (with limited success) to treat prion diseases. It was once a popular heroin adulterant.
Pilocarpine - a parasympatetic antagonist
Pilocarpine is a muscarinic alkaloid obtained from
the leaves of tropical American shrubs from the genus Pilocarpus. It acts as a
muscarinic receptor agonist in the parasympathetic nervous system.
Pilocarpine has been used in the treatment of chronic open-angle glaucoma and acute angle-closure glaucoma for over 100 years. It acts on a subtype of muscarinic receptor (M3) found on the iris sphincter muscle, causing the muscle to contract and produce miosis. This opens the trabecular meshwork through increased tension on the scleral spur. This action facilitates the rate that aqueous humor leaves the eye to decrease intraocular pressure.
Pilocarpine is also used to treat dry mouth (xerostomia). Pilocarpine stimulates the secretion of large amounts of saliva and sweat. It may also cause hypotension and bradycardia in the cardiovascular system, and bronchospasm and increased bronchial secretion in the lungs due to its non-selective muscarinic action.
Pilocarpine is used to stimulate sweat glands in a sweat test to measure the concentration of chloride and sodium that is excreted in sweat. It is used to diagnose cystic fibrosis (CF).
Papaverine - some specific medical uses
Papaverine is approved to treat spasms of the gastointestinal tract, bile ducts and ureter and for use as a cerebral and coronary vasodilator in subarachnoid hemorrhage (combined with balloon angioplasty) and coronary artery bypass surgery. Papaverine may also be used as a smooth muscle relaxant in microsurgery where it is applied directly to blood vessels.
Noscapine - some specific medical uses
Noscapine is used as a cough suppressing agent.
Noscapine is currently under investigation for use in the treatment of several cancers and . In cancer treatment, noscapine appears to interfere with microtubule function, and thus the division of cancer cells in a way similar to the taxanes. Early studies in treatment of prostate cancer are very promising. Studies are currently underway to assess the effectiveness of this drug in cancer and stroke treatment. Noscapine is non-addictive, widely available, has a low side-effect incidence, and is easily administered orally, thus it has great potential for use, especially in developing countries.
Noscapine is also investigated for effectiveness against hypoxic ischemia in stroke patients in stroke treatment. In stroke patients, noscapine blocks the bradykinine b-2 receptors. A 2003 study in Iran showed a dramatic decrease in mortality in patients treated with noscapine.
Noscapine formula - An example of
an alkaloid chemical structure.
Nicotine - possible medical uses
Smoking is dangerous to the health. However,
smokers have certain health benefits in specific situations, probably effected
by nicotine. Nicotine itself may therefor be uses to help cure certain diseases, when admistered without smoking.
However conclusive areas to use nicotine as a cure against diseases are not yet established.
For instance, recent studies suggest that smokers require less frequent repeated revascularization after percutaneous coronary intervention (PCI). Risk of ulcerative colitis has been frequently shown to be reduced by smokers on a dose-dependent basis. The effect is eliminated if the individual stops smoking. Smoking also appears to interfere with development of Kaposi's sarcoma, breast cancer among women carrying the very high risk BRCA gene, preeclampsia, and atopic disorders such as allergic asthma. A plausible mechanism of action in these cases may be nicotine acting as an anti-inflammatory agent, and interfering with the inflammation-related disease process, as nicotine has vasoconstrictive effects.
With regard to neurological diseases, a large body of evidence suggests that the risks of Parkinson's disease or Alzheimer's disease might be twice as high for non-smokers than for smokers. Many such papers regarding Alzheimer's disease and Parkinson's Disease have been published. A plausible mechanism of action in these cases may be the effect of nicotine, a cholinergic stimulant, in decreasing the levels of acetylcholine in the smoker's brain. Parkinson's disease occurs when the effect of dopamine is less than that of acetylcholine.
Recent studies have indicated that nicotine can be used to help adults suffering from Autosomal dominant nocturnal frontal lobe epilepsy. The same areas that cause seizures in that form of epilepsy are also responsible for processing nicotine in the brain.
Nicotine and its metabolites are being researched for the treatment of a number of disorders, including ADHD and Parkinson's Disease.
The therapeutic use of nicotine as a means of appetite-control and to promote weight loss is anecdotally supported by many ex-smokers who claim to put on weight after quitting. However studies of nicotine in mice suggests it may play a role in weight-loss that is independent of appetite. And studies involving the elderly suggest that nicotine affects not only weight loss, but also prevents some weight gain.
(Most of this information is compiled form wikipedia.org)